Universal reaction: 1331TACRhr

Descriptive name:

Demethylation of 31-O-desmethyl-tacrolimus to 13,31-O-Didesmethyl-tacrolimus in hepatocytes

Reaction:

h_r + ahcys_r + 31dmt_r ⇌ amet_r + 1331tacr_r

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_r
H+
-1.0
ahcys_r
S-Adenosyl-L-homocysteine
1.0
amet_r
S-Adenosyl-L-methionine
1.0
1331tacr_r
13,31-O-Didesmethyl-tacrolimus
-1.0
31dmt_r
31-DMT or M-II, 31-O-desmethyl tacrolimus

1331TACRhr in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    1331TACRhr