Gene: 3295_AT1


Descriptive name:

HSD17B4

Model:

Recon3D

Position:

Left: 119452576 – Right: 119541994

Strand:

Plus

Chromosome:

NC_000005.10

Associated reactions:

BiGG ID
Name
Gene reaction rule
C3STKR2r
C-3 sterol keto reductase (zymosterol)
3295_AT1
FAOXC16080x
Beta oxidation of long chain fatty acid
(51_AT1 and 3295_AT1 and 30_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC180x
Beta oxidation of long chain fatty acid
(51_AT1 and 3295_AT1 and 30_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC183806x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1) or (51_AT1 and 30_AT1 and 1962_AT1)
FAOXC18480x
Beta oxidation of long chain fatty acid
(51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC200180x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 30_AT1 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1)
FAOXC2051843x
Beta oxidation of long chain fatty acid
(30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC2242046x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 30_AT1 and 1962_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1)
FAOXC2251836x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 30_AT1 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1)
FAOXC2252053x
Beta oxidation of long chain fatty acid
(51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC226205x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1)
FAOXC240200x_1
Beta Oxidation of Long Chain Fatty Acid
(51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC241181x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 30_AT1 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1)
FAOXC2442246x
Beta oxidation of long chain fatty acid
(51_AT1 and 3295_AT1 and 30_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (3295_AT1 and 30_AT1 and 51_AT2)
FAOXC2452253x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1)
FAOXC2452256x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1)
FAOXC246226x
Beta oxidation of long chain fatty acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1) or (51_AT1 and 30_AT1 and 1962_AT1)
FAOXC260240x_1
Beta Oxidation of Long Chain Fatty Acid
(3295_AT1 and 30_AT1 and 51_AT2) or (51_AT1 and 30_AT1 and 1962_AT1) or (51_AT1 and 3295_AT1 and 30_AT1) or (30_AT1 and 51_AT2 and 1962_AT1)
HACD1x
(S)-3-Hydroxybutanoyl-CoA:NAD oxidoreductase
1962_AT1 or 3295_AT1
HSD17B42x_1
Hydroxysteroid (17-Beta) Dehydrogenase 4
3295_AT1
HSD17B4x
Hydroxysteroid (17-beta) dehydrogenase 4
3295_AT1
PEROXx
Peroxisomal lumped long chain fatty acid oxidation
3295_AT1 and 8310_AT1 and 30_AT1 and 1962_AT1
r0743
Hydroxysteroid (17-beta) dehydrogenase 4 Bile acid biosynthesis EC:1.1.1.35
3295_AT1
r0744
(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl- CoA hydro-lyase Bile acid biosynthesis EC:4.2.1.107
3295_AT1
r1477
Long-Chain-Acyl Coenzyme A Dehydrogenase
(3028_AT1 and 1962_AT1 and 3295_AT1) or (3033_AT1 and 1962_AT1 and 3295_AT1)
RE0512M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3030_AT1 or 3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1 or 3032_AT1
RE0512X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE1525M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1
RE1525X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE1526M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1
RE1526X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE1527M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1
RE1527X
RE1527X
3295_AT1 or 1962_AT1
RE2987X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE2991X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE3005M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1
RE3082X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE3156X
3-Hydroxyacyl Coenzyme A Dehydrogenase
3295_AT1 or 1962_AT1
RE3177M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3030_AT1 or 3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1 or 3032_AT1
RE3178M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3030_AT1 or 3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1 or 3032_AT1
RE3179M
3-Hydroxyacyl Coenzyme A Dehydrogenase
3030_AT1 or 3295_AT1 or 1962_AT1 or 3033_AT1 or 3028_AT1 or 3032_AT1
FAOXC101C8x
Fatty Acid Beta Oxidation (C10:1->C8:0), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC102C81x
Fatty Acid Beta Oxidation (C10:2->C8:1), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC10080x
Beta oxidation of long chain fatty acid
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC10DCC8DCx
Fatty Acid Beta Oxidation (C10Dc->C8Dc)
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC11BRC9BRx
Fatty Acid Beta Oxidation (C11Br->C9Br), Peroxisomal
8310_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC121C10x
Fatty Acid Beta Xoidation (C12:1->C10), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC123C102x
Fatty Acid Beta Oxidation (C12:3->C10:2), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC120100x
Beta oxidation of long chain fatty acid
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC12DCC10DCx
Fatty Acid Beta Oxidation (C12Dc->C10Dc), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC13BRC11BRx
Fatty Acid Beta Oxidation (C13Br->C11Br), Peroxisomal
8310_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC141C121x
Fatty Acid Beta Xoidation (C14:1->C12:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC142C122x
Fatty Acid Beta Oxidation (C14:2->C12:2), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC143C123x
Fatty Acid Beta Oxidation (C14:3->C12:3), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC140120x
Beta oxidation of long chain fatty acid
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC14DCC12DCx
Fatty Acid Beta Oxidation (C14Dc->C12Dc), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC15BRC13BRx
Fatty Acid Beta Oxidation (C15Br->C13Br), Peroxisomal
8310_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC161C141x
Fatty Acid Beta Xoidation (C16:1->C14:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC163C142x
Fatty Acid Beta Oxidation (C16:3->C14:2), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC164C143x
Fatty Acid Beta Oxidation (C16:4->C14:3), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC160140x
Beta oxidation of long chain fatty acid
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC16DCC14DCx
Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC181C161x
Fatty Acid Beta Xoidation (C18:1->C16:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC184C163x
Fatty Acid Beta Oxidation (C18:4->C16:3), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC184C164x
Fatty Acid Beta Oxidation (C18:4->C16:4), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC201C181x
Fatty Acid Beta Xoidation (C20:1->C18:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC205C184x
Fatty Acid Beta Oxidation (C20:5->C18:4), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC221C201x
Fatty Acid Beta Oxidation (C22:1->C20:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC225C204x
Fatty Acid Beta Oxidation (C22:5->C20:4), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC22C20x
Fatty Acid Beta Oxidation (C22->C20), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC241C221x
Fatty Acid Beta Oxidation (C24:1->C22:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC24C22x
Fatty Acid Beta Oxidation (C24->C22), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC61C4x
Fatty Acid Beta Oxidation (C6:1->C4:0), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
FAOXC6C4x
Fatty Acid Beta Oxidation (C6->C4), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC6DCC4DCx
Fatty Acid Beta Oxidation (C6Dc->C4Dc), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC81C61x
Fatty Acid Beta Oxidation (C8:1->C6:1), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC8C6x
Fatty Acid Beta Oxidation (C8->C6), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FAOXC8DCC6DCx
Fatty Acid Beta Oxidation (C8Dc->C6Dc), Peroxisomal
51_AT1 and 1962_AT1 and 3295_AT1 and 30_AT1
FOAXC122C101x
Fatty Acid Beta Oxidation (C12:2->C10:1), Peroxisomal
1962_AT1 and 3295_AT1 and 30_AT1
HMR_1706
3Alpha, 7Alpha, 12Alpha-Trihydroxy-5Beta-Cholest-24-Enoyl Coenzyme A Hydratase
3295_AT1
HMR_3059
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3064
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3068
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3072
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3076
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3096
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3100
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3328
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3332
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3336
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3340
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3344
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3348
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_3352
3-Hydroxyacyl Coenzyme A Dehydrogenase
1962_AT1 or 3295_AT1
HMR_1644
3Alpha, 7Alpha, 12Alpha-Trihydroxy-5Beta-Cholest-24-Enoyl Coenzyme A Hydratase
3295_AT1
3HPVSTETCOAhcx
Beta oxidation of 3-S-hydroxy-pravastatin-CoA to tetranor-CoA in hepatocytes, peroxisomes
51_AT1 or 1962_AT1 or 3295_AT1 or 30_AT1
DEOXFVShc
Formation of deoxy-fluvastatin-dinor
51_AT1 or 1962_AT1 or 3295_AT1 or 30_AT1
PROFVSCOAhc
Beta oxidation (4 cycles) & CYP oxidation of fluvastatin-CoA to des-isoproylpropionic-acid-fluvastatin-CoA in hepatocytes
51_AT1 or 1962_AT1 or 3295_AT1 or 30_AT1 or 1559_AT1

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External database links

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Old identifiers

    3295.1

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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