Reaction: 3HPVSTETCOAhcx

Descriptive name:

Beta oxidation of 3-S-hydroxy-pravastatin-CoA to tetranor-CoA in hepatocytes, peroxisomes

Model:

Recon3D

Reaction:

2.0 coa_x + 2.0 h2o_x + 2.0 nad_x + o2_x + 3hpvscoa_x → 2.0 accoa_x + 2.0 h2o2_x + 2.0 h_x + 2.0 nadh_x + 3hpvstetcoa_x

Metabolites:

Stoichiometry
BiGG ID
Name
2.0
accoa_x
Acetyl-CoA
-2.0
coa_x
Coenzyme A
2.0
h2o2_x
Hydrogen peroxide
-2.0
h2o_x
H2O H2O
2.0
h_x
H+
-2.0
nad_x
Nicotinamide adenine dinucleotide
2.0
nadh_x
Nicotinamide adenine dinucleotide - reduced
-1.0
o2_x
O2 O2
-1.0
3hpvscoa_x
3'-S-hydroxy-pravastatin-CoA
1.0
3hpvstetcoa_x
3'-S-hydroxy-pravastatin-tetranor-CoA

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

51_AT1 or 1962_AT1 or 3295_AT1 or 30_AT1

Genes:

51_AT1 (ACOX1)
3295_AT1 (HSD17B4)
30_AT1 (ACAA1)
1962_AT1 (EHHADH)

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Universal reaction ?

External database links

Old identifiers

    3HPVSTETCOAhcx

3HPVSTETCOAhcx in other models