Reaction: HMGCOARx

Descriptive name:

Hydroxymethylglutaryl CoA reductase (ir)

Model:

iMM1415

Reaction:

2.0 h_x + 2.0 nadph_x + hmgcoa_x → coa_x + 2.0 nadp_x + mev__R_x

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
coa_x
Coenzyme A
-2.0
h_x
H+
2.0
nadp_x
Nicotinamide adenine dinucleotide phosphate
-2.0
nadph_x
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
hmgcoa_x
Hydroxymethylglutaryl CoA C27H39N7O20P3S
1.0
mev__R_x
R Mevalonate C6H11O4

Default bounds:

(0.0, 100000.0)

Objective coefficient:

0.0

Subsystem:

Cholesterol Metabolism

Gene Reaction Rule:

15357

Genes:

15357 (Hmgcr)

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Universal reaction ?

External database links

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Old identifiers

    HMGCOARx

HMGCOARx in other models