Universal reaction: HMGCOARx

Descriptive name:

Hydroxymethylglutaryl CoA reductase (ir)

Reaction:

2.0 h_x + 2.0 nadph_x + hmgcoa_x ⇌ coa_x + 2.0 nadp_x + mev__R_x

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
coa_x
Coenzyme A
-2.0
h_x
H+
2.0
nadp_x
Nicotinamide adenine dinucleotide phosphate
-2.0
nadph_x
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
hmgcoa_x
Hydroxymethylglutaryl CoA C27H39N7O20P3S
1.0
mev__R_x
R Mevalonate C6H11O4

HMGCOARx in BiGG models:

Organism
Model
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Trypanosoma cruzi Dm28c
iIS312
Trypanosoma cruzi Dm28c
iIS312_Amastigote
Trypanosoma cruzi Dm28c
iIS312_Epimastigote
Trypanosoma cruzi Dm28c
iIS312_Trypomastigote
Mus musculus
iMM1415
Homo sapiens
RECON1
Homo sapiens
Recon3D

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Old identifiers

    HMGCOARi_x, HMGCOARx, HMR_4630