Reaction: I2FE2SSfdx

Descriptive name:

ISC 2Fe 2S Synthesis

Model:

iJN1463

Reaction:

2.0 fe2_c + 2.0 iscssh_c + iscu_c + 2.0 fdxr_22_c → 4.0 h_c + 2.0 iscs_c + iscu_2fe2s_c + 2.0 fdxo_22_c

Metabolites:

Stoichiometry
BiGG ID
Name
-2.0
fe2_c
Fe2+ mitochondria
4.0
h_c
H+
2.0
iscs_c
IscS sulfur acceptor protein
-2.0
iscssh_c
IscS with bound sulfur
-1.0
iscu_c
IscU scaffold protein
1.0
iscu_2fe2s_c
IscU with bound [2Fe-2S] cluster
2.0
fdxo_22_c
Ferredoxin oxided form 2Fe 2S
-2.0
fdxr_22_c
Ferredoxin oxided form 2Fe 2S

Default bounds:

(0.0, 999999.0)

Objective coefficient:

0.0

Subsystem:

S_Cofactor_and_Prosthetic_Group_Biosynthesis__FeS_clusters_metabolism

Gene Reaction Rule:

PP_0847 and PP_0844 and (PP_0842 or PP_2435) and PP_0843

Genes:

PP_0847 (fdx)
PP_0843 (iscU)
PP_2435 (iscS-II)
PP_0842 (iscS-I)
PP_0844 (iscA)

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Universal reaction ?

External database links

Old identifiers

    I2FE2SSfdx

I2FE2SSfdx in other models