Reaction: DHFR

Descriptive name:

Dihydrofolate reductase

Model:

iECDH10B_1368

Reaction:

dhf_c + h_c + nadph_c ⇌ nadp_c + thf_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
dhf_c
7,8-Dihydrofolate
-1.0
h_c
H+
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
thf_c
5,6,7,8-Tetrahydrofolate

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cofactor and Prosthetic Group Biosynthesis

Gene Reaction Rule:

ECDH10B_1739 or ECDH10B_0049

Genes:

ECDH10B_1739 (folM)
ECDH10B_0049 (folA)

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Universal reaction ?

External database links

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Old identifiers

    DHFR

DHFR in other models