Reaction: r0463


Descriptive name:

(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Synthesis and degradation of ketone bodies / Valine, leucine and isoleucine degradation / Butanoate metabolism EC:2.3.3.10

Model:

Recon3D

Reaction:

coa_x + h_x + hmgcoa_x ⇌ accoa_x + h2o_x + aacoa_x

Metabolites:


Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cholesterol metabolism

Gene Reaction Rule:

3157_AT1

Genes:

3157_AT1 (HMGCS1)


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External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    r0463

r0463 in other models