Reaction: r0463

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Descriptive name:

(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Synthesis and degradation of ketone bodies / Valine, leucine and isoleucine degradation / Butanoate metabolism EC:2.3.3.10

Model:

Recon3D

Reaction:

coa_x + h_x + hmgcoa_x ⇌ accoa_x + h2o_x + aacoa_x

Metabolites:

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Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cholesterol metabolism

Gene Reaction Rule:

3157_AT1

Genes:

3157_AT1 (HMGCS1)

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