Universal reaction: r0463

Descriptive name:

(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Synthesis and degradation of ketone bodies / Valine, leucine and isoleucine degradation / Butanoate metabolism EC:2.3.3.10

Reaction:

coa_x + h_x + hmgcoa_x ⇌ accoa_x + h2o_x + aacoa_x

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
accoa_x
Acetyl-CoA
-1.0
coa_x
Coenzyme A
1.0
h2o_x
H2O H2O
-1.0
h_x
H+
1.0
aacoa_x
Acetoacetyl-CoA
-1.0
hmgcoa_x
Hydroxymethylglutaryl CoA C27H39N7O20P3S

r0463 in BiGG models:

Organism
Model
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Homo sapiens
Recon3D

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Old identifiers

    r0463