Reaction: 1513DTACRhr

Descriptive name:

Demthylation of 13-O-desmethyl tacrolimus to 13,15-O-didesmethyl tacrolimus in hepatocytes

Model:

Recon3D

Reaction:

h_r + ahcys_r + 13dmt_r → amet_r + 1513tacr_r

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_r
H+
-1.0
ahcys_r
S-Adenosyl-L-homocysteine
1.0
amet_r
S-Adenosyl-L-methionine
-1.0
13dmt_r
13-O-desmethyl tacrolimus, 13-DMT or M-I
1.0
1513tacr_r
13,15-O-didesmethyl tacrolimus

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

Genes:

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Universal reaction ?

External database links

Old identifiers

    1513DTACRhr

1513DTACRhr in other models