Reaction: PI45P3K

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Descriptive name:

Phosphatidylinositol 4,5-bisphosphate 3-kinase

Model:

RECON1

Reaction:

atp_c + pail45p_hs_c → adp_c + h_c + pail345p_hs_c

Metabolites:

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Default bounds:

(0.0, 999999.0)

Objective coefficient:

0.0

Subsystem:

Inositol Phosphate Metabolism

Gene Reaction Rule:

(5290_AT1 and 5295_AT1) or (5293_AT1 and 5295_AT2) or (5290_AT1 and 5295_AT2) or (5294_AT1 and 23533_AT1) or (5290_AT1 and 8503_AT1) or (5296_AT1 and 5293_AT1) or (5296_AT1 and 5290_AT1) or (5291_AT1 and 5295_AT1) or (5295_AT2 and 5291_AT1) or (10870_AT1 and 5294_AT1) or (8503_AT1 and 5291_AT1) or (5295_AT1 and 5293_AT1) or (5293_AT1 and 5295_AT3) or (5293_AT1 and 8503_AT1) or (5291_AT1 and 5295_AT3) or (5295_AT3 and 5290_AT1) or (5291_AT1 and 5296_AT1)

Genes:

8503_AT1 (PIK3R3)
5294_AT1 (PIK3CG)
5295_AT3 (PIK3R1)
5293_AT1 (PIK3CD)
5296_AT1 (PIK3R2)
5295_AT2 (PIK3R1)
5291_AT1 (PIK3CB)
5295_AT1 (PIK3R1)
10870_AT1 (HCST)
5290_AT1 (PIK3CA)
23533_AT1 (PIK3R5)

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