Universal reaction: 6MSMVhep

Descriptive name:

Oxidation of simvastatin to 6-exomethylene lactone form

Reaction:

h_r + nadph_r + o2_r + smv_r ⇌ 2.0 h2o_r + nadp_r + 6msmv_r

Metabolites:

Stoichiometry
BiGG ID
Name
2.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
smv_r
Simvastatin lactone form
1.0
6msmv_r
6'-exomethylene-simvastatin-lactone form

6MSMVhep in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    6MSMVhep