Reaction: r0643

Descriptive name:

(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.1.3

Model:

Recon3D

Reaction:

h2o_m + nad_m + 2mop_m ⇌ 2.0 h_m + nadh_m + HC00900_m

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h2o_m
H2O H2O
2.0
h_m
H+
-1.0
nad_m
Nicotinamide adenine dinucleotide
1.0
nadh_m
Nicotinamide adenine dinucleotide - reduced
-1.0
2mop_m
2-Methyl-3-oxopropanoate
1.0
HC00900_m
Methylmalonate

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Valine, leucine, and isoleucine metabolism

Gene Reaction Rule:

224_AT1 or 217_AT1 or 219_AT1 or 223_AT1 or 501_AT1

Genes:

224_AT1 (ALDH3A2)
501_AT1 (ALDH7A1)
223_AT1 (ALDH9A1)
217_AT1 (ALDH2)
219_AT1 (ALDH1B1)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    r0643

r0643 in other models