Reaction: 3HPVSTETCOAhcm

Descriptive name:

Beta oxidation of 3-S-hydroxy-pravastatin-CoA to tatranor-CoA derivative in hepatocytes, mitochondria

Model:

Recon3D

Reaction:

2.0 coa_m + 2.0 fad_m + 2.0 h2o_m + 2.0 nad_m + 3hpvscoa_m → 2.0 accoa_m + 2.0 fadh2_m + 2.0 h_m + 2.0 nadh_m + o2_m + 3hpvstetcoa_m

Metabolites:

Stoichiometry
BiGG ID
Name
2.0
accoa_m
Acetyl-CoA
-2.0
coa_m
Coenzyme A
-2.0
fad_m
Flavin adenine dinucleotide oxidized
2.0
fadh2_m
Flavin adenine dinucleotide reduced
-2.0
h2o_m
H2O H2O
2.0
h_m
H+
-2.0
nad_m
Nicotinamide adenine dinucleotide
2.0
nadh_m
Nicotinamide adenine dinucleotide - reduced
1.0
o2_m
O2 O2
-1.0
3hpvscoa_m
3'-S-hydroxy-pravastatin-CoA
1.0
3hpvstetcoa_m
3'-S-hydroxy-pravastatin-tetranor-CoA

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

37_AT1 or 3030_AT1 or 3032_AT1

Genes:

3032_AT1 (HADHB)
3030_AT1 (HADHA)
37_AT1 (ACADVL)

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Universal reaction ?

External database links

Old identifiers

    3HPVSTETCOAhcm

3HPVSTETCOAhcm in other models