Reaction: 2HATVLAChc

Descriptive name:

Conversion of 2-hydroxy-atorvastatin-acid to its lactone form in hepatocytes

Model:

Recon3D

Reaction:

atp_c + 2hatvacid_c → amp_c + ppi_c + 2hatvlac_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
amp_c
AMP C10H12N5O7P
-1.0
atp_c
ATP C10H12N5O13P3
1.0
ppi_c
Diphosphate
-1.0
2hatvacid_c
2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid
1.0
2hatvlac_c
2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

Genes:

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Universal reaction ?

External database links

Old identifiers

    2HATVLAChc

2HATVLAChc in other models