Gene: 8714_AT1


Descriptive name:

ABCC3

Model:

Recon3D

Position:

Left: 50634937 – Right: 50691200

Strand:

Plus

Chromosome:

NC_000017.11

Associated reactions:

BiGG ID
Name
Gene reaction rule
BILDGLCURte
Bilirubin beta-diglucuronide transport MDR
4363_AT1 or 1244_AT1 or 8714_AT1
CHOLATEt3
ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1
ESTRONEGLCt
ABC transporter
8714_AT1 or 8714_AT3 or 8714_AT2
r0813
ATP-binding Cassette (ABC) TCDB:3.A.1.208.9
8714_AT1
GCHOLAt3
ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 85320_AT1
TCHOLAt3
ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 85320_AT1
C03990ATP
Transport of Lithocholate, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
C04483t1
Transport of Deoxycholate
8647_AT1 or 8714_AT1 or 85320_AT1
C05463t1
Transport of Taurodeoxycholate
8647_AT1 or 8714_AT1 or 85320_AT1
CE1273t1
Transport of 5Beta-Cholestane-3Alpha, 7Alpha, 12Alpha, 24S, 25-Pentol, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
HC02195te
Transport of Bile Acid, Tauroursodeoxycholate, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
HC02196te
Transport of Bile Acid, Glycoursodeoxycholate, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
HC02194te
Transport of Bile Acid, Ursodeoxycholate, Active Transport
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
HC02220te
Transport of Bile Acid, Sulfochenodeoxycholate, Active Transport
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
DHCHOLESTANATEATP
Transport of 3Alpha, 7Alpha-Dihydroxy-5Beta-Cholestanate, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
THCHOLSTOICATP
Transport of 3Alpha, 7Alpha, 12Alpha-Trihydroxy-5Beta-Cholestanoate, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
XOL7AH3ATP
Transport of 5Beta-Cholestane-3Alpha, 7Alpha, 26-Triol, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
XOL7AONEATP
Transport of 7Alpha-Hydroxycholest-4-En-3-One, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
XOLDIOLONEATP
Transport of 7Alpha, 12Alpha-Dihydroxycholest-4-En-3-One, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
7KILTCHOLATP
Transport of 7-Ketolithocholate, Active Transport
8647_AT1 or 8714_AT1 or 85320_AT1
12DHCHOLabc
12-Dehydrocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
3DHCDCHOLabc
3-Dehydrochenodeoxycholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
3DHCHOLabc
3-Dehydrocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
3DHDCAabc
3-dehydro-deoxycholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1
3DHLCAabc
3-dehydro-lithocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1
7DHCDCHOLabc
7-Dehydrochenodeoxycholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
7DHCHOLabc
7-Dehydrocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
CA24Gte
Glucuronidated bile acid excretion (CA-24G)
8714_AT3 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
CA3Sabc
Cholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
CDCA24Gte
Glucuronidated bile acid excretion (CDCA-24G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
CDCA3Gte
Glucuronidated bile acid excretion (CDCA-3G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
COPROSTabc
Coprostanol ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
DCA24Gte
Glucuronidated bile acid excretion (DCA-24g)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
DCA3Gte
Glucuronidated bile acid excretion (DCA-3G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
DCA3Sabc
Deoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
GCA3Sabc
Glycocholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
GCDCA3Sabc
Glycochenodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
GDCA3Sabc
Glycodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
GUDCA3Sabc
Glycoursodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
HCA24Gte
Glucuronidated bile acid excretion (HCA-24G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
HCA6Gte
Glucuronidated bile acid excretion (HCA-6G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
HDCA24Gte
Glucuronidated bile acid excretion (HDCA-24G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
HDCA6Gte
Glucuronidated bile acid excretion (HDCA-6G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
HYOCHOLabc
Hyocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1
ICDCHOLabc
Isochenodeoxycholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
ISOCHOLabc
Isocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
LCA24Gte
Glucuronidated bile acid excretion (LCA-24G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
LCA3Gte
Glucuronidated bile acid excretion (LCA-3G)
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 9429_AT1
LCA3Sabc
Lithocholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
TCA3Sabc
Taurocholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
TCDCA3Sabc
Taurochenodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
TDCA3Sabc
Taurodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
THYOCHOLabc
Taurohyocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1
TUDCA3Sabc
Tauroursodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
UCHOLabc
Ursocholic acid ABC bile acid transporter
8714_AT3 or 8647_AT1 or 8714_AT2 or 8714_AT1 or 1244_AT1 or 10257_AT1
UDCA3Sabc
Ursodeoxycholic acid 3-sulfate ABC bile acid transporter
8714_AT3 or 8714_AT2 or 8714_AT1 or 10257_AT1 or 1244_AT1 or 9429_AT1
ACMPGLUTtep
Efflux of acetaminophen-glutathione-conjugate from enterocytes into portal blood
8714_AT1
ACMPGLUTthc
Uptake of acetaminophen-glutathione-conjugate by the hepatocytes
8714_AT1
ACMPGLUtep
Efflux of acetaminophen-glucuronide-conjugate from enterocytes into portal blood
8714_AT1
ACMPGLUthc
Uptake of acetaminophen-glucuronide-conjugate by the hepatocytes
8714_AT1
ACMPthc
Uptake of acetaminophen by the hepatocytes
8714_AT1
MERACMPtep
Efflux of acetaminophen-mercapturate-conjugate from enterocytes into portal blood
8714_AT1
MERACMPthc
Uptake of acetaminophen-mercapturate-conjugate by the hepatocytes
8714_AT1
SULPACMPtev
Efflux of acetaminophen-sulphate into hepatic vein
8714_AT1 or 10257_AT1

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External database links

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Old identifiers

    8714.1

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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