Reaction: FTHFLi

Descriptive name:

Formate-tetrahydrofolate ligase

Model:

RECON1

Reaction:

atp_c + for_c + thf_c ⇌ 10fthf_c + adp_c + pi_c

Metabolites:

Stoichiometry

BiGG ID

Name

1.0

10fthf_c

10-Formyltetrahydrofolate

5,6,7,8-Tetrahydrofolate

Default bounds:

(-999999.0, 999999.0)

Objective coefficient:

0.0

Subsystem:

Folate Metabolism

Gene Reaction Rule:

4522_AT1 or 286297_AT1

Genes:

4522_AT1 (MTHFD1)
286297_AT1

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Universal reaction ?

FTHFLi

External database links

RHEA: 20221, 20222, 20223, 20224
MetaNetX (MNX) Equation: MNXR99672
KEGG Reaction: R00943
EC Number: 6.3.4.3
Reactome Reaction: R-ATH-5696839, R-ATH-6801456, R-BTA-5696839, R-BTA-6801456, R-CEL-5696839, R-CEL-6801456, R-CFA-5696839, R-CFA-6801456, R-DDI-5696839, R-DDI-6801456, R-DME-5696839, R-DME-6801456, R-DRE-5696839, R-DRE-6801456, R-GGA-5696839, R-GGA-6801456, R-HSA-5696839, R-HSA-6801456, R-MMU-5696839, R-MMU-6801456, R-OSA-5696839, R-OSA-6801456, R-RNO-5696839, R-RNO-6801456, R-SCE-5696839, R-SCE-6801456, R-SPO-5696839, R-SPO-6801456, R-SSC-5696839, R-SSC-6801456, R-TGU-5696839, R-TGU-6801456, R-XTR-5696839, R-XTR-6801456

Provided by MetaNetX (CC BY 4.0)

Old identifiers

FTHFL

BiGG Models

Reaction: FTHFLi

Descriptive name:

Model:

Reaction:

Metabolites:

Default bounds:

Objective coefficient:

Subsystem:

Gene Reaction Rule:

Genes:

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Universal reaction ?

External database links

Old identifiers

FTHFLi in other models