Universal reaction: TMDS3

Descriptive name:

Thymidylate synthase (FAD dependent)

Reaction:

dump_c + h_c + mlthf_c + nadph_c ⇌ dtmp_c + nadp_c + thf_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
dtmp_c
DTMP C10H13N2O8P
-1.0
dump_c
DUMP C9H11N2O8P
-1.0
h_c
H+
-1.0
mlthf_c
5,10-Methylenetetrahydrofolate
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
thf_c
5,6,7,8-Tetrahydrofolate

TMDS3 in BiGG models:

Organism
Model
Clostridioides difficile 630
iCN900
Mycobacterium tuberculosis H37Rv
iEK1008
Synechococcus elongatus PCC 7942
iJB785
Thermotoga maritima MSB8
iLJ478
Synechocystis sp. PCC 6803
iSynCJ816

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Old identifiers

    TMDS2, TMDS3