Universal reaction: HMGCOAS

Descriptive name:

Hydroxymethylglutaryl CoA synthase

Reaction:

coa_c + h_c + hmgcoa_c ⇌ aacoa_c + accoa_c + h2o_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
aacoa_c
Acetoacetyl-CoA
1.0
accoa_c
Acetyl-CoA
-1.0
coa_c
Coenzyme A
-1.0
h_c
H+
1.0
h2o_c
H2O H2O
-1.0
hmgcoa_c
Hydroxymethylglutaryl CoA C27H39N7O20P3S

HMGCOAS in BiGG models:

Organism
Model
Methanosarcina barkeri str. Fusaro
iAF692
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Mus musculus
iMM1415
Saccharomyces cerevisiae S288C
iMM904
Saccharomyces cerevisiae S288C
iND750
Lactococcus lactis subsp. cremoris MG1363
iNF517
Staphylococcus aureus subsp. aureus N315
iSB619
Bacillus subtilis subsp. subtilis str. 168
iYO844
Staphylococcus aureus subsp. aureus USA300_TCH1516
iYS854
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

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Old identifiers

    HMGCOAS, HMGCOASi