Universal reaction: FPGS4

Descriptive name:

Folylpolyglutamate synthetase (DHF)

Reaction:

4.0 atp_c + dhf_c + 4.0 glu__L_c ⇌ 4.0 adp_c + 4.0 h_c + 4.0 pi_c + 5dhf_c

Metabolites:

Stoichiometry
BiGG ID
Name
4.0
adp_c
ADP C10H12N5O10P2
-4.0
atp_c
ATP C10H12N5O13P3
-1.0
dhf_c
7,8-Dihydrofolate
-4.0
glu__L_c
L-Glutamate
4.0
h_c
H+
4.0
pi_c
Phosphate
1.0
5dhf_c
Pentaglutamyl folate (DHF)

FPGS4 in BiGG models:

Organism
Model
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Mus musculus
iMM1415
Homo sapiens
RECON1

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External database links

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Old identifiers

    FPGS4