Universal reaction: CYP2R1

Descriptive name:

Vitamin D3 25-hydroxylase

Reaction:

h_c + nadph_c + o2_c + vitd3_c ⇌ h2o_c + nadp_c + 25hvitd3_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
h2o_c
H2O H2O
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_c
O2 O2
1.0
25hvitd3_c
25-Hydroxyvitamin D3
-1.0
vitd3_c
Calciol; (+)-Vitamin D3

CYP2R1 in BiGG models:

Organism
Model
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Homo sapiens
Recon3D

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Old identifiers

    CYP2R1, RE1303C