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Universal reaction: AKGDm


Descriptive name:

2-oxoglutarate dehydrogenase

Reaction:

akg_m + coa_m + nad_m ⇌ co2_m + nadh_m + succoa_m

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
akg_m
2-Oxoglutarate
1.0
co2_m
CO2 CO2
-1.0
coa_m
Coenzyme A
-1.0
nad_m
Nicotinamide adenine dinucleotide
1.0
nadh_m
Nicotinamide adenine dinucleotide - reduced
1.0
succoa_m
Succinyl-CoA

AKGDm in BiGG models:

Organism
Model
Plasmodium berghei
iAM_Pb448
Plasmodium cynomolgi strain B
iAM_Pc455
Plasmodium falciparum 3D7
iAM_Pf480
Plasmodium knowlesi strain H
iAM_Pk459
Plasmodium vivax Sal-1
iAM_Pv461
Homo sapiens
iAT_PLT_636
Cricetulus griseus
iCHOv1
Mus musculus
iMM1415
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

  • RHEA: 27786, 27787, 27788, 27789
  • KEGG Reaction: R08549
  • BioCyc: META:2OXOGLUTARATEDEH-RXN
  • Reactome Reaction: R-ATH-71401, R-BTA-71401, R-CEL-71401, R-CFA-71401, R-DDI-71401, R-DME-71401, R-DRE-71401, R-GGA-373042, R-GGA-71401, R-HSA-71401, R-MMU-71401, R-OSA-71401, R-PFA-71401, R-RNO-71401, R-SCE-71401, R-SPO-71401, R-SSC-71401, R-TGU-71401, R-XTR-71401
  • EC Number: 1.2.1.52, 1.2.4.2, 1.8.1.4, 2.3.1.61
  • SEED Reaction: rxn08094
  • MetaNetX (MNX) Equation: MNXR95655

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    AKGDm

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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