Universal reaction: 6HSMVhep

Descriptive name:

Oxidation of simvastatin to 6-beta-hydroxy simvastatin

Reaction:

h_r + nadph_r + o2_r + smv_r ⇌ h2o_r + nadp_r + 6hsmv_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
smv_r
Simvastatin lactone form
1.0
6hsmv_r
6'-beta-hydroxy simvastatin lactone

6HSMVhep in BiGG models:

Organism
Model
Homo sapiens
Recon3D

Report an error on this page ?

External database links

Old identifiers

    6HSMVhep