Universal reaction: 6HMSMVhep

Descriptive name:

Oxidation of 6-exomethylene simvastatin to 6-beta-hydroxy methyl simvastatin

Reaction:

h2o_r + h_r + nadph_r + o2_r + 6msmv_r ⇌ nadp_r + h2o2_r + 6hmsmv_r

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
1.0
h2o2_r
Hydrogen peroxide
-1.0
6msmv_r
6'-exomethylene-simvastatin-lactone form
1.0
6hmsmv_r
6'-beta-hydroxy-methyl-simvastatin-lactone form

6HMSMVhep in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    6HMSMVhep