Universal reaction: 2HATVLACOXDhc

Descriptive name:

Oxidation of atorvastatin lactone to 2-hydroxy-atorvastatin-lactone in hepatocytes

Reaction:

h_r + nadph_r + o2_r + atvlac_r ⇌ h2o_r + nadp_r + 2hatvlac_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
1.0
2hatvlac_r
2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone
-1.0
atvlac_r
Atorvastatin-lactone

2HATVLACOXDhc in BiGG models:

Organism
Model
Homo sapiens
Recon3D

Report an error on this page ?

External database links

Old identifiers

    2HATVLACOXDhc