Universal reaction: 13DMThr

Descriptive name:

Demthylation of tacrolimus to 13-O-desmethyl tacrolimus in hepatocytes

Reaction:

h_r + ahcys_r + tacr_r ⇌ amet_r + 13dmt_r

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_r
H+
-1.0
ahcys_r
S-Adenosyl-L-homocysteine
1.0
amet_r
S-Adenosyl-L-methionine
-1.0
tacr_r
Tacrolimus
1.0
13dmt_r
13-O-desmethyl tacrolimus, 13-DMT or M-I

13DMThr in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    13DMThr