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Universal reaction: 12HTACRhr

Descriptive name:

Oxidation of tacrolimus in hepatocytes

Reaction:

h_r + nadph_r + o2_r + tacr_r ⇌ h2o_r + nadp_r + 12htacr_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
tacr_r
Tacrolimus
1.0
12htacr_r
12-HT or M-VI, 12-hydroxy tacrolimus

12HTACRhr in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    12HTACRhr